Milestone articles have highlighted the frequency and types of statistical errors in research,1–5 yet fundamental errors ...

Background and objective Prior studies have suggested that patients with premature ventricular complexes (PVCs) may have an ...

Diabetes mellitus is highly prevalent in patients with coronary atherosclerosis. As a result of several factors, including a ...

Background A pathway incorporating an option for early discharge based on a single low level of high-sensitivity cardiac troponin I (hs-cTnI) at presentation increases the proportion of patients ...

Background Anomalous aortic origin of a coronary artery (AAOCA) is a congenital abnormality of the origin or course of coronary artery. The clinical manifestations of coronary artery anomalies vary in ...

Introduction Bicuspid aortic valve (BAV) affects 1% of the general population. NOTCH1 was the first gene associated with BAV. The proportion of familial and sporadic BAV disease attributed to NOTCH1 ...

Background Emerging evidence suggests associations between air pollution, multimorbidity, and atrial fibrillation (AF), but their interplay remains unclear. We evaluated these relationships in a ...

Introduction Cardiovascular benefits deriving from physical activity are well known, but it is unclear whether physical activity trajectories in late life are associated with different risks of ...

Background Bicuspid aortic regurgitation (AR) is common in younger patients who often do not meet guideline-based criteria for aortic valve (AV) surgery at diagnosis. However, identifying early ...

Objective The Appropriate Use Criteria (AUC) has been used to identify individuals who are likely to benefit from percutaneous coronary intervention (PCI) for stable ischaemic heart disease. However, ...

Knowledge of the anatomy of the ‘conduction tissues’ of the heart is a 20th century phenomenon. Although controversies still continue on the topic, most could have been avoided had greater attention ...