Somatic hypermutation was originally hypothesized to be a two-step process, initiated by cleavage of the DNA within the mutating region, and subsequently resolved by error-prone repair 9.

B cell germinal centres achieve a balance between clonal expansion and sequence diversification by suppressing somatic hypermutation during proliferative clonal bursts.

Abstract Background Patients in chronic somatic diseases are often accompanied with depression and anxiety, remission of which may be observed in the third or fourth week after applying common ...

Abstract Background Patients in chronic somatic diseases are often accompanied with depression and anxiety, remission of which may be observed in the third or fourth week after applying common ...

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