Boltz-2 is an open-source biomolecular model achieving near-FEP accuracy with 1000x faster predictions for structure and binding affinity. Quiver AI Summary MIT and Recursion have released Boltz-2 ...

The MIT model predicts molecular binding affinity at newfound speed and accuracy, offering a powerful tool for commercial drug discovery.

Knowledge about the molecular basis of SARS-CoV-2 infection is incipient. However, recent experimental results about the virus interactome have shown that th ...

By further fusing the geometric attributes and structural features of molecules, we can elevate the performance of molecular representation. To realize this, we present a novel geometry-augmented ...

To investigate in detail whether SARS-CoV-2 mRNA vaccination induces a comprehensive and non-specific reprogramming of monocyte-derived macrophages, which is a key characteristic of innate immune ...

About Phoenix Molecular Designs PhoenixMD is a privately held clinical-stage biopharmaceutical company focused on developing first-in-class inhibitors against RSK, for cancer and inflammation. Their ...

The global health crisis triggered by the SARS-CoV-2 virus has highlighted the urgent need for effective treatments. As existing drugs are not specifically targeted at this virus, there is a growing ...

Google DeepMind releases AlphaFold 3's source code to academics, marking a significant advance in AI-powered molecular biology and drug discovery, while balancing open science with commercial ...

Synopsis The mechanism of β-arrestin (βarr2) pre-activation by PIP 2 has not yet been fully understood. This study suggests that PIP 2 induces allosteric conformational changes in βarr2, which ...

Explore how the linear molecular geometry of carbon dioxide affects its physical properties and role in our environment.