Each enzyme has an active site, which is where the reaction takes place. The lock and key model explains how enzymes work: The enzyme is like a "lock". The substrate (the molecule it reacts with ...

Each enzyme molecule has a special place called the active site where another molecule, called the substrate, fits. The substrate goes through a chemical reaction and changes into a new molecule ...

The diagram shows how this works ... breaks the weak hydrogen bonds holding the enzyme’s unique active site shape. Enzyme–substrate complexes can no longer form as the substrates no longer ...