Scientists have long struggled to target proteins that lack defined structure and are involved in cancer, neurodegenerative ...

These enzymes ... the structure of uMtCK, the scientists captured images using cryogenic electron microscopy (cryo-EM). This technology enables investigators to create 3D images of proteins ...

Life has evolved over billions of years, adapting to the changing environment. Similarly, enzymes—proteins that speed up ...

Anfinsen, based on his studies of the ribonuclease enzyme, proposed that all the information needed to determine the tertiary structure of a protein is encoded in its amino acid sequence. “It is ...

Enzymes are generally proteins but also include catalytic DNA and catalytic RNA. As effective biological catalysts, enzymes work by lowering a reaction’s activation energy barrier, thereby ...

DNA repair proteins act like the body's editors ... Although previous studies have mapped parts of Pol-theta's structure, the enzyme's interactions with DNA weren't well understood.

7 However, artificial intelligence (AI) has substantially improved protein structure prediction based on amino acid ... this strategy to engineer protein-based vaccines, antibodies, and enzymes with ...

Similarly, enzymes -- proteins that speed up biochemical reactions ... temperatures is linked to the flexibility of its molecular structure. However, the precise molecular mechanisms behind ...

SARS-CoV-2, the virus responsible for COVID-19, infects cells by binding its spike protein to angiotensin-converting enzyme 2 (ACE2 ... However, mutations in the spike protein can alter its structure, ...