For the matter of expanded indications of FDA-approved therapies, the authors presented alteplase (Activase, Genentech) and tenecteplase (TNKase, Genentech) as contrasting, viable answers to ...

Alteplase is also sold by Boehringer in the UK under the Actilyse brand. According to NICE, Metalyse costs less than alteplase, so could save the NHS millions of pounds when used as a stroke ...

Fibrin-specific plasminogen activator TNKase (tenecteplase) is the first stroke medicine approved by the FDA in nearly 30 years, joining Roche/Genentech's Activase (alteplase), which is the only ...

Many observational studies in patients with stroke (including both ischemic and ICH) have found that use of prehospital notification to the destination ED is associated with faster time to ...

Ischemic stroke Arterial collateral status and treatment effect of intravenous alteplase thrombolysis prior to endovascular treatment in patients with anterior circulation large vessel occlusion: ...