The Chicago Cubs (60-42) visit the South Side of Chicago to face the Chicago White Sox (37-66) Friday in the first game of a 3-game interleague series. First pitch from Rate Field is at 7:40 p.m. ET. Let's analyze BetMGM Sportsbook's MLB odds around the Cubs vs. White Sox odds and make our expert MLB picks and predictions for the best bets.

BOTTOM LINE: The Chicago Cubs lead 1-0 in a three-game series with the Boston Red Sox. Chicago is 31-16 at home and 58-39 overall. The Cubs have a 44-7 record in games when they out-hit their opponents.

Chicago Cubs rookie Cade Horton Horton left Sunday’s game in the sixth inning with a 1-0 lead, but the Cubs lost 6-1. It was Horton’s fourth no-decision of the season.