HIV-1 reverse transcriptase inhibitors are crucial in the treatment of HIV-1 infections, as they target the reverse transcriptase enzyme that the virus uses to replicate its genetic material.

HIV-1 reverse transcriptase inhibitors are crucial components in the treatment of HIV, a virus that leads to acquired immune deficiency syndrome (AIDS). These inhibitors are categorized into two ...

Summary: While single mutations confer resistance to earlier nonnucleoside reverse transcriptase inhibitors (NNRTIs), etravirine exhibited an increased barrier to resistance by requiring multiple ...

NRTI = nucleoside reverse transcriptase inhibitor, NNRTI = nonnucleoside reverse transcriptase inhibitor, PI = protease inhibitor. b While this has not been reflected in the IAS-USA and BHIVA ...

Pseudoscience has recently re-emerged in the U.S. While much of it concerns vaccines, an "oldie" is again making the rounds: ...

Breakthrough Therapy designation Doravirine/islatravir (Merck) Combination of a non-nucleoside reverse transcriptase inhibitor and a nucleoside reverse transcriptase translocation inhibitor ...

ViiV Healthcare, the global specialist HIV company majority owned by GSK, with Pfizer and Shionogi as shareholders, today announced that the European Commission has authorised Vocabria (cabotegravir ...

The new data – presented at the IDWeek congress yesterday – found that the pairing of MSD's experimental nucleoside reverse transcriptase translocation inhibitor islatravir with Gilead's ...

Welcome to the Merck & Company Q4 sales and earnings conference call. [Operator instructions] This call is being recorded.

Q4 2024 Earnings Call Transcript February 4, 2025 Merck & Co., Inc. misses on earnings expectations. Reported EPS is $1.72 ...

There are several classes of antiretrovirals, which are defined by what step of viral replication they target: nucleoside reverse transcriptase inhibitors; non-nucleoside reverse transcriptase ...