TFE3 fusion proteins are the oncogenic drivers of translocation renal cell carcinoma but their mechanism of action remains ...

As per the National Health Service (NHS) recommends that men and women between 19 to 64 years should take a daily dose of 300 mg and 270 mg of magnesium, respectively.

Notably, microglia spatially associated with amyloid plaques exhibited increased expression of TREM2 and ApoE compared to ...

Furthermore, functional genes associated with sulfur metabolism, nitrogen fixation, and oxidative phosphorylation displayed marked temporal variations within the aeration pond, underscoring the ...

Mitochondria generate ATP through oxidative phosphorylation, and also have a central role in apoptosis. Activated brown adipose tissue takes up large amounts of branched-chain amino acids (BCAAs ...

Here the authors show that the protective role of IL-1 in a fatal systemic murine model of infection involves metabolic modulation including inhibition of oxidative phosphorylation and hypoxia via ...

This duality in energy production—where CSCs can switch between glycolysis and oxidative phosphorylation (OXPHOS)—enables them to adapt to varying micro-environmental conditions, contributing to their ...

A U of A researcher recently created a new class of drugs that targets and kills cancer cells with less damage to healthy ...

Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder with a rapidly increasing global prevalence. It is primarily characterized by insulin resistance, β-cell dysfunction, and impaired ...

1Department of Molecular and Systems Biology, Dartmouth Geisel School of Medicine, Lebanon, New Hampshire.