Background Although typically a late feature of gout, tophi may present early in the course of disease. The aim of this study was to identify factors associated with the presence of early ...

It usually affects the big toe but can occur in any joint, including the ankle. After years of having gout, tophi (lumps of uric acid) can form beneath the skin around the ankles. Retrocalcaneal ...

However, given the likely contribution of higher comorbidities to poorer health outcomes among respondents, comorbid status may be confounded with gout flares and tophi in the analyses.

Gout can be extremely painful and can affect other joints including the ankle, fingers ... of urate crystals in bumps or nodules called tophi which generally are not painful but during flares ...

and dissolve tophi in gout and tophaceous gout patients, today announced the completion of enrollment for its pivotal global Phase 3 REDUCE 2 trial. "We would like to thank the gout community for ...

Arthrosi Therapeutics, Inc., a late-stage biotechnology company developing a potentially best-in-class, highly potent and selective next generation URAT1 inhibitor to reduce serum urate (sUA) levels, ...