In the moderate stage of PD, patients begin to experience diminished benefit from antiparkinson medications. This phenomenon is often called narrowing of the therapeutic window. Motor fluctuations ...

This trial enrolled 747 PD patients with early disease who were in need of levodopa therapy. Patients could be on stable dosages of other antiparkinson on medications except amantadine.

Objective To determine the economic impact of medication non-adherence across multiple disease groups. Design Systematic review. Evidence review A comprehensive literature search was conducted in ...