TFE3 fusion proteins are the oncogenic drivers of translocation renal cell carcinoma but their mechanism of action remains ...
Defects in the oxidative phosphorylation (OXPHOS) system — the final biochemical pathway in the production of ATP — result in devastating, mainly multisystem diseases. The OXPHOS system is ...
A U of A researcher recently created a new class of drugs that targets and kills cancer cells with less damage to healthy ...
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Time to update textbooks on electron transport chain in mitochondria, researchers say"Until a few years ago, we were sure that mitochondria produced ATP via oxidative phosphorylation in the intermembrane space, where the inner and outer membranes interact. This has changed.
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Researchers find B cells drive responses of other immune cells, can be modified to prevent multiple sclerosis symptomsThey found that these actions can all be traced back to metabolic dysregulation in a process within the B cells called oxidative phosphorylation, a type of mitochondrial respiration. Researchers ...
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