These decrements in HRQOL vary across the spectrum of clinical phenotypes according to the presence and frequency of gout symptoms and signs. Patients with confirmed tophi and more frequent acute ...

Skin ulcerations caused by gouty tophi were found on the left third toe and the right second toe (Figure). This case can serve as a reminder that patients with hyperuricemia should be treated with ...

The big toe is the most common joint for a gout ... It is a sign of advanced or chronic gout. When tophi affect the small joints of the thumbs and fingers, physical changes and limited movement ...

Tophi are a collection of uric acid crystals that accumulate underneath the skin. Gout occurs from high levels of uric acid ...

prevent urate deposition (tophi) in various body tissues and influence the progressive course of chronic tophaceous gout. With accumulating experience in the continuous use of uricosuric agents ...

The present study quantifies the impact of the presence of tophi and frequency of acute gout attacks on health-related quality of life (HRQOL), productivity, and healthcare resource utilization.