The present study quantifies the impact of the presence of tophi and frequency of acute gout attacks on health-related quality of life (HRQOL), productivity, and healthcare resource utilization.

There was a history of gout for many years. Tophi were present on the joints of both hands and the left great toe. The urine had a specific gravity of 1.014 and gave a ++ test for albumin.

Tophi are a collection of uric acid crystals that accumulate underneath the skin. Gout occurs from high levels of uric acid ...

Background Although typically a late feature of gout, tophi may present early in the course of disease. The aim of this study was to identify factors associated with the presence of early ...

Patients with gout often start out with pain in their big toe to a severity that the simple ... of urate crystals in bumps or nodules called tophi which generally are not painful but during ...

and dissolve tophi in gout and tophaceous gout patients, today announced the completion of enrollment for its pivotal global Phase 3 REDUCE 2 trial. Arthrosi Logo (PRNewsfoto/Arthrosi Therapeutics ...