Although the vast majority of expressed sequence tags (ESTs) and single nucleotide polymorphisms (SNPs) may never prove to be important medically or agriculturally, some could play an important ...

How did it become possible to sequence the 3 billion base pairs in the human genome? More than a quarter of a century’s worth of work from hundreds of scientists made such projects possible.

The authors combined parallel radiation hybrid (RH) mapping analysis with express sequence tag (EST) sequence information and a bioinformatic methodology called COMPASS (comparative mapping by ...