Among patients with stroke clots in large and medium vessels not planned for endovascular therapy (EVT), those who got alteplase at 4.5-24 hours after stroke onset were disproportionately more ...

40% of participants treated with alteplase had little to no disability after 90 days, compared to 26% of those who received standard care - a 54% higher chance of functional recovery. Less than 3% ...

Recent study presented at the American Stroke Association's International Stroke Conference 2025 suggests that the clot-dissolving medication alteplase could significantly improve recovery ...

The activity and sterility of reconstituted alteplase solution and the effectiveness of an alteplase dose-escalation protocol for the clearance of midlinecatheter and central-venous-access device ...

The fibrinolytic activity of alteplase remained at >90% (compared with the standard solution) for the initial 48 hours at 2 °C, regardless of whether the solution had first been frozen (Table 1).