The Astros won Game 1 of the series 3-0, despite 8.0 innings from Paul Skenes and one earned run allowed. The Pirates have now lost three of the past four games, while the Astros have gone 7-2 over the past nine and 3-1 in the previous four.

Preview the June 4 matchup between the Houston Astros and Pittsburgh Pirates with odds over/under, game spread, betting lines and more.

The Pirates dropped 2 of 3 games at the San Diego Padres, losing 6-4 as +133 underdogs in the Sunday finale with the Over (8.5) hitting. Pittsburgh held an 83.9% win probability, according to ESPN Analytics, leading 4-1 with 1 out in the bottom of the sixth inning Sunday -- but was outscored 5-0 the rest of the way.