Saint Xavier University is a private Catholic university in Chicago, Illinois, United States. Founded in 1846 by the Sisters of Mercy, the university enrolls 3,749 students. Saint Xavier University was founded as a women's college by the Sisters of Mercy in 1846 at the request of Bishop William Quarter. With the City of Chicago less than 10 years old, the religiou…Saint Xavier University is a private Catholic university in Chicago, Illinois, United States. Founded in 1846 by the Sisters of Mercy, the university enrolls 3,749 students. Saint Xavier University was founded as a women's college by the Sisters of Mercy in 1846 at the request of Bishop William Quarter. With the City of Chicago less than 10 years old, the religious sisters, under the guidance of Mother Mary Francis Xavier Warde, R.S.M., established Saint Francis Xavier Female Academy. The academy, which would later become Saint Xavier College, and finally Saint Xavier University, was the first Mercy College and is the oldest chartered college in the city of Chicago.